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Category: Publications

Delivery of SP-101 restores CFTR function in human CF airway epithelial cultures and drives hCFTRΔR transgene expression in the airways of ferrets

Poster: 621: Administration of SP-101 and doxorubicin results in robust and durable human cystic fibrosis transmembrane conductance regulator minigene transgene expression in the airways of ferrets and corrects human cystic fibrosis airway epithelia in vitro. North American Cystic Fibrosis Conference 2022

Poster 643: Delivery of gp64-pseudotyped lentivirus carrying codon-optimized CFTR provides improved functional restoration in human CF airway epithelial cultures. North American Cystic Fibrosis Conference 2022

Poster: 672:  SP-101 activity increases in a dose dependent manner to both vector and doxorubicin dose. North American Cystic Fibrosis Conference 2022

Abstract: 672:  SP-101 activity increases in a dose dependent manner to both vector and doxorubicin dose. North American Cystic Fibrosis Conference 2022

Abstract 643: Delivery of gp64-pseudotyped lentivirus carrying codon-optimized CFTR provides improved functional restoration in human CF airway epithelial cultures. North American Cystic Fibrosis Conference 2022

Abstract: 621: Administration of SP-101 and doxorubicin results in robust and durable human cystic fibrosis transmembrane conductance regulator minigene transgene expression in the airways of ferrets and corrects human cystic fibrosis airway epithelia in vitro. North American Cystic Fibrosis Conference 2022

<a href="https://spirovant.com/wp-content/uploads/2022/03/NACFC-SP-101_POSTER_Master-9-22-2181-Read-Only-1.pdf">Katherine Excoffon: Delivery of SP-101 restores CFTR function in human CF airway epithelial cultures and drives hCFTRΔR transgene expression in the airways of ferrets. North American Cystic Fibrosis Conference 2021. – Poster</a>

Katherine Excoffon: Delivery of SP-101 restores CFTR function in human CF airway epithelial cultures and drives hCFTRΔR transgene expression in the airways of ferrets. North American Cystic Fibrosis Conference 2021. – Video

<a href="https://www.mdpi.com/2073-4425/10/3/218"> Lentiviral Vectors for the Treatment and Prevention of Cystic Fibrosis Lung Disease </a>

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